Acute Necrosis of the Liver in Pregnancy

Noftji ? F' Jolly: This patient, a woman, aged 27, who was normally domiciled in Pre&n ern Ireland, first came to Bristol in February, 1956, when she was five weeks atthe j s^e ^ad had no Previous children. She was seen at Southmead Hospital given that month by Dr. P. Phillips. The date of her last menstrual period was Hth qS ?th January, 1956 from which it was calculated that she would be due on PreSsu ct?ber. The height of the fundus corresponded with these dates. Her blood A few j an<^ urine were normal, there was no oedema, and her weight was 7 stone, bribed apS ^ater there was slight leucorrhoea for which acetarsol pessaries were preHer ' Regular ante-natal supervision was carried out by her general practitioner. On Pressure remained at 120/70 mm. Hg. or less and there was no albuminuria. to August, at the 30th week of gestation her blood pressure was found to have agai, to ̂ ?/9? rnm. Hg. and she had swelling of the feet and hands. She was referred After Phillips who advised more rest and suggested Sodium amytal gr. 3 nightly. lQllal s\ IS|.t.^ere was no further rise in blood pressure, no albuminuria and only occasOn j ^ n? the feet and ankles. ^thn u^ePtember' s^e was Emitted to Southmead Hospital, 36 weeks pregnant Pain bef1 t0 *n earty labour. There had been backache for ten days and some cari0Us t?re micturition. In appearance she was a thin sallow girl with greying hair, Pressureeeth and a marked squint. The heart, lungs and urine were normal, the blood iestati0n Was 160/100 mm. Hg. and the fundus height corresponded to 34 weeks